It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Pregnant women and chloroquine When taking aralen should i be using an antiacid Chloroquine and proguanil during pregnancy Gi problems with hydroxychloroquine See 17 for PATIENT COUNSELING INFORMATION and Medication 3 3 Revised HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use KEVZARA ® safely and effectively. See full prescribing information for KEVZARA. KEVZARA sarilumab injection, for subcutaneous use Initial U. S. Approval 2017 PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Drugs that inhibit CYP3A4 enzymes may increase plasma levels of hydroxychloroquine. Proton pump inhibitors may antagonize the immunomodulating effects of hydroxychloroquine. 7. Additional known interactions between hydroxychloroquine and coadministered drugs may be described in the FDA-approved Full Prescribing Information for Plaquenil. 9. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil prescribing info HIGHLIGHTS OF PRESCRIBING INFORMATION immune-mediated dermatologic., Plaquenil Hydroxychloroquine Sulfate Wiki hydroxychloroquine WebMD provides information about interactions between Plaquenil Oral and selected-cyp2d6-inhibitors-metoprolol. metoprolol succinate US prescribing information. AstraZeneca LP March, 2011. Interactions between Plaquenil Oral and selected-cyp2d6-inhibitors.. Hydroxychloroquine Information for Providers AIDSinfo. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. PlaquenilHydroxychloroquine Learn about Plaquenil's Dosage, Side Effects and indications. PHILIPPINES. Basic Prescribing Info Basic Prescribing Info.