Additionally, another exception occurred while executing the custom error page for the first exception. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Hydroxychloroquine interference with warfarin Chloroquine transfection what is Retinal toxicity is a very rare side effect of the hydroxychloroquine therapy, but when it has occurred, vision loss may be permanent and may progress even years after the cessation of medication. Patients would be examined every 3 months, then annually, until they are stabled. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Plaquenil retinal toxicity treatment Protecting your eyesight when taking Plaquenil Lupus., Rx Side Effects New Plaquenil Guidelines and More. Plaquenil geneticHidroxiklorokin plaquenil eksisozlukPlaquenil and kidney stonesHydroxychloroquine hypokalemia The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Retinal Toxicity in Patients Treated With Hydroxychloroquine.. Because no effective treatment for retinal hydroxychloroquine toxicity currently exists, cessation of administration of the drug is the only way to manage the condition. The decision to discontinue treatment must be made in conjunction with the patient℉s internist or rheumatologist. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine is an excellent drug with low systemic toxicity and should not be stopped without firm evidence of retinal damage.” Communication key. “If I see a patient with evidence of Plaquenil toxicity,” said Dr. Mieler, “I telephone the referring doctor—usually a rheumatologist—in front of the patient and ask, ‘Can.