Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. The drug plaquenil Plaquenil for crest syndrome Does plaquenil help osteoarthritis People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Does Hydroxychloroquine Have Side Effects? Like all medications, there is the risk of side effects. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Dosage of plaquenil RA and Hydroxychloroquine How Effective is it for., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Differential diagnosis for plaquenil retinopathyNatural medicine comparable to hydroxychloroquineChloroquine phosphate and coralPlaquenil herx symptomsCan plaquenil cause joint pain The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Plaquenil Risk Calculators. RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis.. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Why Use. Use in an outpatient setting for adult patients taking hydroxychloroquine Plaquenil. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Mg/kg base not to exceed 400 mg 310 mg base PO weekly, starting 2 weeks before exposure and continued for 4 weeks after departure from area With prolonged therapy, obtain CBCs periodically.