Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil pharmacology Mechanism of action of chloroquine in malaria treatment Plaquenil birth Ra hydroxychloroquine The recommended hydroxychloroquine dosage for rheumatoid arthritis is 400 mg to 600 mg a day by mouth as a single dose or divided into two separate doses. However, once a good response is being maintained with hydroxychloroquine, doses may be reduced to 200 mg to 400 mg per day for maintenance. Feb 19, 2020 PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients Dibasic Calcium Phosphate, Hydroxypropyl Methylcellulose, Magnesium Stearate, Polyethylene glycol 400, Polysorbate 80, Corn Starch, Titanium Dioxide. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine sulfate tablets usp 200 mg uses Hydroxychloroquine Sulfate Monograph for Professionals., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Plaquenil for sjogrens Pharmacokinetics Following a single 200 mg oral dose of Hydroxychloroquine sulfate tablets to healthy males, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. In the same study, the plasma peak concentration was 50.3 ng/mL reached in 3.74 hours with a half-life of 2963 hours 123.5 days. HYDROXYCHLOROQUINE SULFATE TABLETS, USP. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine - Wikipedia. PrPLAQUENIL® Hydroxychloroquine Sulfate Tablets USP 200 mg ACTIONS AND CLINICAL PHARMACOLOGY PLAQUENIL hydroxychloroquine sulfate tablets belongs to the 4-aminoquinoline class. PLAQUENIL has been beneficial for patients with rheumatoid arthritis and lupus erythematosus, especially chronic discoid lupus. DOSAGE AND ADMINISTRATION. One tablet of 200 mg of hydroxychloroquine sulfate, USP is equivalent to 155 mg base. 400 mg =310 mg base on exactly the same day of each week. the weekly suppressive dosage is 5 mg, calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight. One tablet of 200 mg of hydroxychloroquine sulfate is equivalent to 155 mg base. Malaria Suppression—In adults, 400 mg =310 mg base on exactly the same day of each week. In infants and children, the weekly suppressive dosage is 5 mg, calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight.