But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Does plaquenil affect blood pressure Plaquenil toxicity eye oct Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Dec 29, 2004 "Natural" alternative to Plaquenil. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. CONDITIONS OF USE The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Is there a natural drug substitute for plaquenil What can substitute plaquenil hydroxychloroquine., Natural" alternative to Plaquenil. - HealthBoards Coming off plaquenilHydroxychloroquine tablets in hindiPlaquenil from canadaCan i drink alcohol while taking plaquenil Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil Oral Interactions with Other Medication. Plaquenil hydroxychloroquine Alternatives & Similar Drugs.. May 07, 2019 Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. Methotrexate Remove Methotrexate from your drug comparison. Celebrex celecoxib Remove Celebrex from your drug comparison. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. May also be prescribed off label for Sjogren's Syndrome. I'm still searching for that magic "all natural" replacement since I cannot tolerate plaquenil. The stomach, liver & eye complications are too great to bear. and that's at the lowest, lowest dose. Anyway, guess I need to get into some deeper research about exactly what this drug does, and see if there's an herb out there that may help.