It leads to fluid buildup, especially in your legs. Other symptoms of congestive heart failure: Deep vein thrombosis (DVT) and thrombophlebitis: If you have DVT, it means there's a blood clot in a vein in your leg. When that happens, it's called a pulmonary embolism, and it can be life-threatening. Hydroxychloroquine sulfate 200 mg tab s Chloroquine side effects anxiety Chloroquine mode of action malaria PLAQUENIL is a synthetic Quinilone, belongs in the Floro Quinilone family which has a black box warning by the FDA. I did not this at the time i took it. Previously had bad tendon damage with Cipro. Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs. loss of hearing. lower back or side pain. noisy breathing. painful or difficult urination. red irritated eyes. red skin lesions, often with a purple center. severe mood or mental changes. sore throat sores, ulcers, or white spots on the lips or in the mouth Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. One of the first symptoms of DVT or thrombophlebitis is one swollen leg (especially the calf), as blood pools in the area. In thrombophlebitis, also called superficial thrombophlebitis, clots form closer to the surface of the skin and aren't likely to break off. Plaquenil leg swelling How to Avoid Having Heavy Legs & Swelling of Ankles Healthfully, Plaquenil Side Effects - GoodRx Plaquenil usoMarine chloroquine phosphate Sep 13, 2019 large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs; loss of hearing; lower back or side pain; noisy breathing; painful or difficult urination; red irritated eyes; red skin lesions, often with a purple center; severe mood or mental changes; sore throat sores, ulcers, or white spots on the lips or in the mouth Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine Plaquenil. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. There is no Foot, leg, and ankle swelling reported by people who take Plaquenil yet. This review analyzes which people have Foot, leg, and ankle swelling with Plaquenil. It is created by eHealthMe based on reports from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes. People with myositis caused by a virus usually have symptoms of a viral infection, such as runny nose, fever, cough and sore throat, or nausea and diarrhea. But the symptoms of viral infection may go away days or weeks before myositis symptoms begin. Some people with myositis have muscle pain, but many do not.