Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus (SLE or "Lupus") and rheumatoid arthritis. Hydroxychloroquine in canada Plaquenil and atorvastatin Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction. My Lupus is mild so I'm going the. User Reviews for Hydroxychloroquine to treat Systemic Lupus Erythematosus. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Overview. During my last visit, I told him I was struggling with fatigue, so he prescribed Plaquenil hydroxychloroquine. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. When effective, it can decrease damage to the tissues of the joints, skin and other organs in the body. Although chloroquine is sometimes used, the preferred antimalarial drug is hydroxychloroquine due to its greater safety. It is not possible at the present time to explain precisely why hydroxychloroquine is effective in various rheumatic diseases. Plaquenil for lupus reviews fatigue Is extreme fatigue a side effect of Plaquenil - NRAS, Hydroxychloroquine User Reviews for Systemic Lupus. Chloroquine during pregnancyAlternativesto taking plaquenilHydroxychloroquine alopeciaHow does plaquenil affect eyes Hallucinated, broke out in rashes and crying spells. It was the worst 2 months of these side effects I've ever had in my life! Got off of it and I feel back to normal. My Lupus is mild so I'm going the holistic route. Plant based diet, acupuncture, juicing. I feel good and will take minor aches and fatigue any day than being on plaquenil. Beware! Plaquenil Drug and Medication User Reviews on RxList. Things that Changed My Life with Lupus Fatigue, Part 3. Best medication to treat Lupus fatigue?" Lupus Community.. I am 99% sure that the Plaquenil has not caused your fatigue. If anything, it’s Lupus OR psychosomatic. Plaquenil is a slow-acting drug which is why you take it long term. It honestly takes on average 1 to 3 months to work and be built up in your system, which is why you typically have a 3-6 month review after being prescribed it. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. My dr told me that she thinks that I probably have Fibromyalgia and an Undifferentiated Connective Tissue Disorder suspected Lupus. She gave me Plaquenil for the pain that I have been having, and a steroid pack in the interm.