I really didn't have all that much to eat yesterday either, so maybe that was it. I don't think I am going to take it anymore at night before bed. Plaquenil lowef platelets 1989 honduras chloroquine Hydroxychloroquine vs chloroquine phosphate Plaquenil for ankylosing spondylitis User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Their sister company Zentiva now make Hydroxy which has the exact same fillers etc in it as Plaquenil which is why so many people can tolerate that one much better, the proof is in the pudding! I'm sorry you are having such a problem with it. I didn't have a ton of nightmares, but the ones I had were pretty memorable, extremely unpleasant, and unlike any dreams I have ever had before or since! If they had continued indefinitely, I would probably have stopped the Plaquenil - but they did gradually stop after about 4-5 months. These meds make it tough, some on a completely empty stomach, some on a full stomach and the rest somewhere in between! I had lunch with my friend who was in my nightmares and I felt anxious afterwards like something was going to happen to us. Hydroxychloroquine and why nightmares Hydroxychloroquine MedlinePlus Drug Information, Hydroxychloroquine - nightmares? Hope everyone has. Plaquenil and puffy face Nightmares; sensation of spinning; shakiness and unsteady walk; uncontrolled eye movements; unsteadiness, trembling, or other problems with muscle control or coordination; vomiting; For Healthcare Professionals. Applies to hydroxychloroquine compounding powder, oral tablet. Cardiovascular Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil and nightmares. Will you have Nightmares with Hydroxychloroquine sulfate - eHealthMe. If plaquenil helps you with other symptoms, it's worth it, though. Can't have the immune system running wild and taking over! I may have to go back to taking it myself, eventually. I wish there were more info on how high a dose really has an effect. For example, people who take it for malaria prevention only take 400 mg per week, and it does. Nightmares sensation of spinning shakiness and unsteady walk uncontrolled eye movements unsteadiness, trembling, or other problems with muscle control or coordination vomiting Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Data from case series and retrospective and open-label studies support the use of hydroxychloroquine in the treatment of extensive cutaneous sarcoidosis Chong 2005, Jones 1990, Modi 2008. Contraindications. Known hypersensitivity to hydroxychloroquine, 4-aminoquinoline derivatives, or any component of the formulation.