In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil maculopathy mechanisms Is plaquenil still the go drug for lupud Macular Society is the trading name of the Macular Disease Society. A charity registered in England and Wales 1001198, Scotland SC042015. 1123 Isle of Man. A company limited by guarantee, registered in England No. 2177039. Or is any of the treatments used known to cause it? I have had a large number of drusen in my retina for about 10 year. The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied. Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil treatment with macular degeneration Hydroxychloroquine Plaquenil Toxicity and Recommendations., Macular degeneration and lupus" Lupus Community. Hydroxy chloroquine 200 mgHydroxychloroquine hyperpigmentationHydroxychloroquine sun skin Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine-Induced Retinal Toxicity - American.. What about Plaquenil and Macular Degeneration? - Inspire. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. If you have any questions or want more information about any drug on this list and its possible links to macular degeneration, talk to your prescribing physician and/or ophthalmologist. You may also want to discuss whether the use of a drug on this list outweighs the increased risk of side effects compared with other treatments. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications.