Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine maculopathy oct Chloroquine mammalian cells Plaquenil and Mood swings - a study from real-world data. Summary Mood swings is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Pain. Anxiety and Plaquenil. maybe mood disorder, maybe huge stressful life that needs to be cut back. not saying you cant blame every single uncomfortable thing in life on lupus, but lupus is not the entire you. menopause is a wild ride thru hell with or without lupus, cancer, grief, indigestion, bee sting - check for other issues as well. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and mood Plaquenil Side Effects on Your Eyes and Vision, Anxiety and Plaquenil Has anyone experienced mood. Hydroxychloroquine site mayoclinic.orgWhere can i buy plaquenilHydroxychloroquine sulfate and psoriasisPlaquenil flying saucer Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Rx Side Effects New Plaquenil Guidelines and More - American Academy.. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of antimalarials as a sort of “lupus life insurance.” Other potential side effects include but are not limited to nausea, changes in mood, muscle weakness, skin pigmentation and anemia. While the drug may be used during pregnancy, the potential benefits and risks should be discussed with your doctor. In summary, if you have Sjögren’s, hydroxychloroquine may be an option to help your symptoms. Have you had your thyroid tested recently? Swinging hypothyroid can cause mood swings, depression and constipation. I took Plaquenil for six years and am really not sure whether I suffered any side effects or not. I think it may have contributed to tinnitus and I came off i9t in case it was contributing to balance issues.