As of this time, there is no known effective pharmaceutical treatment, although it is much needed for patient contracting the severe form of the disease. The aim of this systematic review was to summarize the evidence regarding chloroquine for the treatment of COVID-19. Chloroquine blood to plasma ratio Malaria tablets chloroquine Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. Chloroquine is not embryo- and fetotoxic when used at the usual dose for malaria prophylaxis or for a three-day treatment of a typical malaria attack McGready 2002, Phillips-Howard 1996. Current evidence does not suggest fetal ocular toxicity when chloroquine was used as antimalarian medication during pregnancy review by Osadchy 2011. Chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be Chloroquine seems to be effective in limiting the replication of SARS-Co V-2 (virus causing COVID-19) in vitro. We included six articles (one narrative letter, one in-vitro study, one editorial, expert consensus paper, two national guideline documents) and 23 ongoing clinical trials in China. Chloroquine review Chloroquine in Cancer Therapy A Double-Edged Sword of Autophagy, Chloroquine - an overview ScienceDirect Topics Plaquenil biologicPlaquenil retinopathy to reverseCan hydroxychloroquine cause diarrhea Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury. Chloroquine - LiverTox - NCBI Bookshelf. Chloroquine drug Britannica. Chloroquine Aralen - Side Effects, Dosage, Interactions.. Compare Chloroquine vs Hydroxychloroquine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Chloroquine rated 10.0/10 vs Hydroxychloroquine rated 6.7/10 in overall patient satisfaction. COVID-19 coronavirus disease 2019 is a public health emergency of international concern. As of this time, there is no known effective pharmaceutical Chloroquine has been proposed several times for the treatment of acute viral diseases in humans without success. • The outcomes of some current clinical trials of chloroquine in China have been announced, without access to the data. • Peer review of the results and an independent assessment of the potential benefit for patients are essential.