Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Eye tests required for plaquenil Chloroquine chemistry Plaquenil and blood glucose Plaquenil skin changes If there is a favorable response, therapy is tapered to 50mg every 2 weeks for 3 months, then every 3 weeks for 3 months and then finally to a maintenance monthly dose. No response after a total of 1g should be considered a treatment failure. Monthly gold should be continued indefinitely. I was told from the start by my rheumatologist I would have to have eye exams including visual field exams every six months due to the plaquenil therapy. My first two exams did include these tests. But my next six month appointment is coming up, and they told me I didn't need the visual field test this time so the appointment would be shorter. Plaquenil is a pretty widely used drug so I figure she should have an opinion on it. I would feel more comfortable having the baseline exam done first BUT I am pretty eager to get started on it ASAP as my eye is starting to bug me due to the morphea that is slowly spreading. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Baseline reading for plaquenil therapy PowerPoint. Update on Plaquenil Testing, Plaquenil therapy and eye exams. - Eye Care - MedHelp Chloroquine phosphate for malariaChloroquine primaquine combinationSide effects of starting plaquenilPlaquenil oct damage Baseline Screening. But it was for alleged Plaquenil related eye toxicity, and believe me, attornies will grab any guideline they can as "Standard-of-Care" if it suits their case. And lucky for me, my lawsuit was dropped after the plaintiff was seen reading the newspaper and his cell phone in the waiting room of his lawyer's office. My Take on New Ocular Screening Guidelines for Plaquenil.. Starting Plaquenil BEFORE Eye Exam? - Scleroderma - Inspire. I have lichen planopilaris and the doctor is recommending.. Baseline Examination All patients should have a baseline ophthalmologic examination within the first year of initiating HCQ or CQ therapy with thorough risk factor assessment and fundus examination of the macula to rule out underlying disease. Baseline visual field and SD OCT are recommended if abnormalities are present e.g. macular lesions, glaucoma, etc that could affect screening tests. Research has shown that your risk of developing retinopathy is higher the longer you are taking Plaquenil. In fact, the incidence of retinal toxicity rises sharply in people that have taken it between 5 and 7 years. As a result, baseline testing should occur within the first year of taking the drug and then annually at the five-year mark. A baseline ocular examination is recommended within the first year of starting PLAQUENIL. The baseline exam should include best corrected distance visual acuity BCVA, an automated threshold visual field VF of the central 10 degrees with retesting if an abnormality is noted, and spectral domain ocular coherence tomography SD-OCT.