It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Dosage of plaquenil for rheumatoid arthritis Dermatomyositis rash and plaquenil recent findings The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. The question of safety of hydroxychloroquine during pregnancy remains unanswered. There are anecdotal reports of exacerbations of psoriasis with hydroxychloroquine. Supply. Tablets, 200 mg. Dosage. Initially, 400 mg in single or divided doses; after a good response 4 to 12 weeks, maintain at 200 mg/d. Leflunomide Arava Action Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine 200 mg for rheumatoid arthritis Hydroxychloroquine Plaquenil Success, Reviews and Side., RA and Hydroxychloroquine How Effective is it for. Osteoarthritis joint nodules hydroxychloroquinePlaquenil eye effects Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine Plaquenil. Hydroxychloroquine Plaquenil - Rheumatoid Arthritis. Hydroxychloroquine Reviews Everyday Health. A controlled, double blind, parallel group, long term study of hydroxychloroquine sulphate in the treatment of rheumatoid arthritis, comparing daily doses of 200 mg and 400 mg, is described. The trial involved 54 patients with moderate disease activity. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. For the treatment of RA, hydroxychloroquine is typically taken by mouth once daily at 200-400 mg, although it can be taken at a higher dose. A loading dose of 1,200 mg daily, given for 6 weeks may decrease the time to clinical response. However, experts debate that this higher dosage may increase the risk of toxicity.