Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Does hydroxychloroquine help with fatigue Chloroquine target life cycle Clinical pharmacokinetics and metabolism of chloroquine Chloroquine medscape Ive been taking Hydroxychloroquine since december. As im not too good at taking tabs anyway Im trying to steer clear of steroids. So I tried this one I agree with mrschewie it SOMETIMES takes the edge off the pain but I get very nauseous and try to take after food when I can eat. I still suffer from severe headache fatigue insomnia and back pain. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. Oct 24, 2013 After just 4 days on Plaquenil, I had severe stomach cramps, no appetite, GERD pain, diarrhea and a migraine. Not sure that the migraine was related but it happened on day 4. After contacting my Rheumatologist, I was told to stop taking the drug. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine and stomach pain Plaquenil and stomach pain DailyStrength, Stomach problems with Plaquenil • Johns Hopkins Arthritis. Plaquenil drug eruptionChloroquine cdc malaria The exact hydroxychloroquine mechanism of action is unclear, although it does work to interrupt the communication of immune system cells to decrease swelling, pain, and joint damage. 1, 2, 3, 5 From the community “My Rheumatologist recently put me on Hydroxychoroquine for treating osteoarthritis and joint cysts in my hands and every other. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Stomach cramps from Plaquenil - what to do? Lupus Forums at.. Plaquenil, stomach pain and diarrhea. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. Aug 26, 2016 While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. This sort of upset usually does not occur with commercial Plaquenil. Your doctor can ensure that you receive this version of the medication by writing “do not substitute” on your script. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. stomach cramps;. less pain, fewer lupus-related rashes, and a better ability to move around.