Derm Net NZ Medical Editor: Dr Delwyn Dyall-Smith, Dermatologist, Wagga Wagga, NSW, Australia. However, following an identical dose of hydroxychloroquine and chloroquine, tissue levels of chloroquine are 2.5 times those of hydroxychloroquine. Derm Net NZ Editor in Chief: Adjunct Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Hydroxychloroquine is preferred due to its safer profile. K63 ub after chloroquine Chloroquin Hydroxychloroquine sulfate advers reactions In 1984, I wrote my first prescription for the antimalarial drug, hydroxychloroquine Plaquenil, for a 28-year-old woman with SLE. She was considerably overweight, with inflammatory arthritis and a photosensitive rash, and I worried that oral corticosteroids would tip her over into diabetes. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Lupus skin rash is the most common complaint among Lupus patients. And the Lupus skin rash treatments that actually work are too few and far in between. Lupus skin rash was once the worst symptom for me. As a woman in her 20’s just diagnosed with lupus, I was desperate to look not only normal but cared a lot about looking good. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. If there is a of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Plaquenil face rash Hydroxychloroquine DermNet NZ, Hydroxychloroquine - Wikipedia Plaquenil sleep problemsPlaquenil liver damage tests Simultaneous worsening of the skin rash while taking Plaquenil and improvement from sunlight would definitely not be expected for the diagnosis of cutaneous lupus. The rash resembled psoriasis clinically, and two additional biopsies confirmed the diagnosis. Psoriasis Associated with Plaquenil Hydroxychloroquine - Dr.. Lupus Skin Rash Treatments That Actually Work - Blog. Plaquenil Oral Uses, Side Effects, Interactions.. PLEASE HELP! I have been on Plaquenil well the generic form-- hydroxychloroquine since October, and for the past about 2 weeks, I have been SEVERELY skin turns red, and it feels like something is biting me. It's bad around my ankles and the tops of my feet, my arms, and I get red blotches and spots on my chest. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Has anyone ever experienced a rash on their face from plaquenil? I had to go without my plaquenil long story about insurance etc. and this red rash that I had on my face went away. I know plaquenil can cause rashes in the sun but I was wearing sunscreen and it was winter. I wasn't outside much. I haven't tried wearing a hat all the time.