Calcium is essential for the normal function of organs, cells, muscles, and nerves. It’s also important in blood clotting and bone health. Hypercalcemia makes it hard for the body to carry out its normal functions. Chloroquine induces degradation Hydroxychloroquine skin rash treatment Undetected hypercalcemia and hypercalciuria can cause nephrocalcinosis, renal stones, and renal failure. Corticosteroids cause prompt reversal of the metabolic defect. Chloroquine, hydroxychloroquine, and ketoconazole are the drugs that should be used if the patient fails to respond or develops dangerous side effects to corticosteroid therapy. As a treatment for sarcoidosis, the antimalarial drug hydroxychloroquine Plaquenil® is most likely to be effective in patients with dermatologic involve-ment, joint manifestations and hypercalcemia. Due to poten-tial macular toxicity, it is recommended that patients on hydroxychloroquine have an eye examination every 6-12 months. Methotrexate. Hypercalcemia developed in a patient undergoing long-term hemodialysis, and she was found to have noncaseating granulomas on lymph node biopsy. Hydroxychloroquine was administered as therapy for the hypercalcemia. Over 24 weeks of treatment with the drug, concentrations of calcium and 1,25-dihydroxyvitamin D returned to normal. High calcium can affect the electrical system of the heart, causing abnormal heart rhythms. Extremely high levels of calcium can be life-threatening. Plaquenil hypercalcemia Plaquenil Sarcoidosis Hypercalcemia, SARCOIDOSIS TREATMENT GUIDELINES Plaquenil and hypoglycemiaRheumatoid arthritis guidelines hydroxychloroquine monotherapyDoes hydroxychloroquine stop hair lossPlaquenil use in macular degen Plaquenil belongs to a group of drugs called antimalarials or antiprotozoals. Protozoa are unicellular organisms that can cause various infections in human body. This medication is widely use to manage malaria and is also indicated for the treatment of liver disease caused by certain protozoa. Plaquenil Hydroxychloroquine Oral Uses, Dosage & Side Effects. Hydroxychloroquine treatment of hypercalcemia in a patient with.. Hypercalcemia - Cleveland Clinic. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hypercalcemia is a condition in which the calcium level in your blood is above normal. Too much calcium in your blood can weaken your bones, create kidney stones, and interfere with how your heart and brain work. Hypercalcemia is usually a result of overactive parathyroid glands. These four tiny glands are situated behind the thyroid gland. Hydroxychloroquine treatment of hypercalcemia in a patient with sarcoidosis undergoing hemodialysis. Barré PE, Gascon-Barré M, Meakins JL, Goltzman D. Hypercalcemia developed in a patient undergoing long-term hemodialysis, and she was found to have noncaseating granulomas on lymph node biopsy.