It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Aao 2016 plaquenil Les éffets secondaires de plaquenil au long cours Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long will plaquenil stay in your system How long does Hydroxychloroquine stay in your system?, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Plaquenil blurry vision years after stoppingHydroxychloroquine porphyria cutanea tardaPlaquenil warningsAfraid to try plaquenil With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Taking Plaquenil for Rheumatoid Arthritis. How long does it take for plaquenil to leave your system?. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. How Long Does It Take for Medicine to Absorb? Credit Kristian Sekulic/E+/Getty Images According to About.com, how long medicine takes to absorb into the stomach depends on the type of medication, whether it is taken with food or on an empty stomach, and the ability of the medication to pass into the bloodstream. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the.