This illustration shows melanoma cells extending from the surface of the skin into the deeper skin layers. Melanoma, the most serious type of skin cancer, develops in the cells (melanocytes) that produce melanin — the pigment that gives your skin its color. Hydroxychloroquine lower white blood cells Plaquenil and lupus flares Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. The exact cause of all melanomas isn't clear, but exposure to ultraviolet (UV) radiation from sunlight or tanning lamps and beds increases your risk of developing melanoma. Melanoma can also form in your eyes and, rarely, inside your body, such as in your nose or throat. Does plaquenil cause melanoma HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical uses, and., Common and Rare Side Effects for Plaquenil Oral Plaquenil effects on eyes Whether you or someone you love has cancer, knowing what to expect can help you cope. From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. Melanoma Skin Cancer Risk Factors Melanoma Risk Factors. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg 6-8 hours later and then 400 mg at 24 hours and 48 hours. The dose for malaria prevention is 400 mg every week starting 1 or 2 weeks before exposure and for 4 weeks after leaving the high risk area. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Acral-lentiginous melanoma is a rare form of melanoma that can occur under a fingernail or toenail. It can also be found on the palms of the hands or the soles of the feet. It's more common in black people and in other people with darker skin pigment. Melanoma in the mouth, digestive tract, urinary tract or vagina. If you are taking any drugs that can cause a certain type of heartbeat that is not normal prolonged QT interval. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure. This is not a list of all drugs or health problems that interact with Plaquenil hydroxychloroquine.